| Identification | Back Directory | [Name]
p-Nitrobenzyl mesylate | [CAS]
39628-94-9 | [Synonyms]
p-Nitrobenzyl mesylate
4-Nitrobenzyl Mesylate
4-Nitrobenzyl methanesulfonate
p-Nitrobenzyl mesylate, Alkylation reagent
Benzenemethanol, 4-nitro-, 1-methanesulfonate | [Molecular Formula]
C8H9NO5S | [MOL File]
39628-94-9.mol | [Molecular Weight]
231.23 |
| Chemical Properties | Back Directory | [Boiling point ]
449.4±28.0 °C(Predicted) | [density ]
1.431±0.06 g/cm3(Predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
DMSO: 100 mM | [form ]
A solid | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
4-Nitrobenzyl Mesylate is used to develop thiophosphate ester epitopes which can be recognized by antibodies. 4-Nitrobenzyl Mesylate can be used to study protein phosphorylation and map signaling network architecture. | [Biological Activity]
p-Nitrobenzyl mesylate (PNBM) is a thiol-specific alkylating reagent for direct kinase substrate identification. p-Nitrobenzyl mesylate (PNBM) alkylates thiophosphorylated proteins to form thiophosphate ester epitopes th at can be detected by thiophosphate-ester-specific antibody by immunoblottingimmunoprecipitation or immunoaffinity purification. |
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