| Identification | Back Directory | [Name]
ALATERNIN | [CAS]
39723-40-5 | [Synonyms]
Catharticin
Rhamnocitrin 3-O-β-D-rhamninoside
4H-1-Benzopyran-4-one, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→6)-β-D-galactopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy- | [Molecular Formula]
C34H42O19 | [MOL File]
39723-40-5.mol | [Molecular Weight]
754.69 |
| Chemical Properties | Back Directory | [Melting point ]
185-189 °C(Solv: methanol (67-56-1)) | [Boiling point ]
1061.4±65.0 °C(Predicted) | [density ]
1.68±0.1 g/cm3(Predicted) | [pka]
6.04±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO4/H2O2) with an IC50 value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC50 value of 4.02 μM[1]. | [References]
[1] Jung H A, et al. Alaternin and emodin with hydroxyl radical inhibitory and/or scavenging activities and hepatoprotective activity on tacrine-induced cytotoxicity in HepG2 cells[J]. Archives of pharmacal research, 2004, 27: 947-953. DOI:10.1007/BF02975849 |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|