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400044-47-5

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400044-47-5 Structure

400044-47-5 Structure

Identification	Back Directory
[Name] UK-396082
[CAS] 400044-47-5
[Synonyms] UK-396082 1H-Imidazole-4-propanoic acid, α-(3-aminopropyl)-1-propyl-, (αS)-
[Molecular Formula] C12H21N3O2
[MOL File] 400044-47-5.mol
[Molecular Weight] 239.32

Chemical Properties	Back Directory
[Boiling point ] 467.3±40.0 °C(Predicted)
[density ] 1.17±0.1 g/cm3(Predicted)
[pka] 3.85±0.21(Predicted)

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[Uses] UK?396082 is a potent thrombin activated fibrinolytic inhibitor (TAFI) inhibitor. UK?396082 increases plasmin activity and induces a parallel decrease in ECM levels. UK?396082 can be used in research of chronic kidney disease (CKD)[1].
[References] [1] Atkinson JM, et, al. An inhibitor of thrombin activated fibrinolysis inhibitor (TAFI) can reduce extracellular matrix accumulation in an in vitro model of glucose induced ECM expansion. Matrix Biol. 2013 Jun 24;32(5):277-87. DOI:10.1016/j.matbio.2013.01.006

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