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400628-16-2

400628-16-2 Structure

400628-16-2 Structure
IdentificationBack Directory
[Name]

STAT3-IN-24, cell-permeable
[CAS]

400628-16-2
[Synonyms]

STAT3-IN-24, cell-permeable
Stat3 Peptide Inhibitor, cell-permeable, Stat3 inhibitor
Hazard InformationBack Directory
[Uses]

STAT3-IN-24, cell-permeable (PpYLKTK-mts) is a STAT3 peptide inhibitor. STAT3-IN-24, cell-permeable inhibits recruitment of STAT3 to Jak2 and phosphorylation of Y705, thus preventing the dimerization and the nuclear translocation of STAT3[1].
[References]

[1] Buettner C, et al. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006 Jul;4(1):49-60. DOI:10.1016/j.cmet.2006.04.014
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