| Identification | Back Directory | [Name]
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]- | [CAS]
402855-07-6 | [Synonyms]
Afatinib M
6-Nitro-4-[(3-chloro-4-fluorophenyl)amino]-7-[(R)-(tetrahydr...
N-(3-chloro-4-fluorophenyl)-6-nitro-7-[(3R)-oxolan-3-yl]oxyquinazolin-4-amine
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]-
(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine (Afatinib Impurity)
Afatinib impurity 20/4-QuinazolinaMine,N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]- | [Molecular Formula]
C18H14ClFN4O4 | [MOL File]
402855-07-6.mol | [Molecular Weight]
404.78 |
| Hazard Information | Back Directory | [Uses]
(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is an intermediate used in the preparation of afatinib ant it’s impurities. Afatinib(A355300) is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
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