| Identification | Back Directory | [Name]
MDL-12,330A HYDROCHLORIDE | [CAS]
40297-09-4 | [Synonyms]
MDL-12330A
MDL-12,330A HCL
MDL 12230A HYDROCHLORIDE
MDL-12,330A HYDROCHLORIDE
MDL-12,330A, Hydrochloride - CAS 40297-09-4 - Calbiochem
CIS-N-(2-PHENYLCYCLOPENTYL)AZACYCLOTRIDEC-1-EN-2-AMINE HCL
CIS-N-(2-PHENYLCYCLOPENTYL)AZACYCLOTRIDEC-1-EN-2-AMINE HYDROCHLORIDE
N-[(1R,2R)-2-phenylcyclopentyl]-1-azacyclotridecen-2-amine:hydrochloride
CIS-N-(2-PHENYLCYCLOPENTYL)-AZACYCLOTRIDEC-1-EN-2-AMINE MONOHYDROCHLORIDE
(±)-N-[(1R*,2R*)-2-Phenylcyclopentyl]-azacyclotridec-1-en-2-aminehydrochloride | [Molecular Formula]
C23H37ClN2 | [MDL Number]
MFCD00210204 | [MOL File]
40297-09-4.mol | [Molecular Weight]
377.01 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
hot 0.1 N HCl: 0.50 mg/mL | [form ]
solid | [color ]
white | [InChI]
1S/C23H36N2.ClH/c1-2-4-6-11-18-23(24-19-12-7-5-3-1)25-22-17-13-16-21(22)20-14-9-8-10-15-20;/h8-10,14-15,21-22H,1-7,11-13,16-19H2,(H,24,25);1H/t21-,22-;/m0./s1 | [InChIKey]
CKOPQUCSDBVAQG-VROPFNGYSA-N | [SMILES]
Cl[H].C1CCCCCN=C(CCCCC1)N[C@H]2CCC[C@H]2c3ccccc3 |
| Hazard Information | Back Directory | [Uses]
MDL-12,330A hydrochloride has been used as an inhibitor of adenylyl cyclase to block cyclic AMP signaling in mesenchymal stem/stromal cells (MSC). It has also been used as an adenylyl cyclase blocker to test its effect on the locomotor activity based on tail suspension test (TST) in mice. | [Biochem/physiol Actions]
MDL-12,330A is a cycloalkyl lactamimide that acts as a voltage-gated potassium channel blocker (KV) leading to extension of action potential duration (APD) and favoring insulin secretion. It also blocks calcium (Ca2+)?entry. |
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Sigma-Aldrich
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Merck Millipore
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http://www.merckmillipore.com |
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Merck KGaA
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