ChemicalBook--->CAS DataBase List--->40454-21-5

40454-21-5

40454-21-5 Structure

40454-21-5 Structure
IdentificationBack Directory
[Name]

GUANYL-CYS-OH
[CAS]

40454-21-5
[Synonyms]

iqb-782
GUANYL-CYS-OH
GUANYL-L-CYSTEINE
n-amidinocysteine
n-guanyl-cysteine
N-Guanyl-L-cysteine
N-amidino-L-cysteine
N-ALPHA-GUANYL-L-CYSTEINE
n-(aminoiminomethyl)-l-cystein
N-(Aminoiminomethyl)-L-cysteine
n-guanidine-beta-mercaptoalanine
L-Cysteine, N-(aminoiminomethyl)-
(R)-2-Guanidino-3-mercaptopropanoic acid
[EINECS(EC#)]

254-925-1
[Molecular Formula]

C4H9N3O2S
[MDL Number]

MFCD00672377
[MOL File]

40454-21-5.mol
[Molecular Weight]

163.2
Chemical PropertiesBack Directory
[Boiling point ]

325.8±52.0 °C(Predicted)
[density ]

1.66±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

3.01±0.10(Predicted)
[Cosmetics Ingredients Functions]

HAIR WAVING OR STRAIGHTENING
Hazard InformationBack Directory
[Uses]

IQB-782 is a cysteine derivative. IQB-782 has inhibition for thrombin activatable fibrinolysis inhibitor (TAFI), with an Ki(app) of 0.14 μM. IQB-782 shows a potent mucolytic-expectorant activity[1][2].
[References]

[1] Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71. DOI:10.1016/j.thromres.2004.12.023
[2] Moratalla R, et al. Pharmacological study of the new mucolytic drug N-guanyl-cysteine. Arzneimittelforschung. 1986 Jun;36(6):918-23. PMID:88747
Safety DataBack Directory
[Toxicity]

LD50 oral in rat: > 6gm/kg
Spectrum DetailBack Directory
[Spectrum Detail]

GUANYL-CYS-OH(40454-21-5)1HNMR
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