| Identification | Back Directory | [Name]
N-(2-CHLOROETHYL)-N-ETHYL-2-BROMOBENZYLAMINE HYDROCHLORIDE | [CAS]
40616-75-9 | [Synonyms]
DSP-4
DSP-4 HYDROCHLORIDE
Neurotoxin DSP 4 (hydrochloride)
N-(2-CHLOROETHYL)-N-ETHYL-2-BROMOBENZYL&
2-BROMO-N-(2-CHLOROETHYL)-ETHYLBENZYLAMINE
N-(2-CHLOROETHYL)-N-ETHYL-2'-BROMOBENZYLAMINO HCL
N-(2-CHLOROETHYL)-N-ETHYL-2'-BROMOBENZYLAMINE HCL
N-(2-CHLOROETHYL)-N-ETHYL-2-BROMOBENZYLA MINE HYDRO
o-bromo-n-(2-chloroethyl)-n-ethylbenzylaminehydrochloride
o-bromo-n-(2-chloroethyl)-n-ethyl-benzylaminhydrochloride
N-ETHYL-N-(2-CHLOROETHYL)-2-BROMOBENZYLAMINE HYDROCHLORIDE
N-(2-CHLOROETHYL)-N-ETHYL-2-BROMOBENZYLAMINE HYDROCHLORIDE
N-(2-CHLOROETHYL)-N-ETHYL-2'-BROMOBENZYLAMINE HYDROCHLORIDE
DSP-4, N-Ethyl-N-(2-chloroethyl)-2-bromobenzylamine hydrochloride | [Molecular Formula]
C11H16BrCl2N | [MDL Number]
MFCD00043241 | [MOL File]
40616-75-9.mol | [Molecular Weight]
313.06 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
H2O: soluble48mg/mL | [form ]
solid | [color ]
white | [Water Solubility ]
H2O: 48mg/mL
0.1 M NaOH: 7mg/mL
ethanol: soluble | [BRN ]
4020910 | [InChI]
1S/C11H15BrClN.ClH/c1-2-14(8-7-13)9-10-5-3-4-6-11(10)12;/h3-6H,2,7-9H2,1H3;1H | [InChIKey]
NDDRNRRNYOULND-UHFFFAOYSA-N | [SMILES]
Cl[H].CCN(CCCl)Cc1ccccc1Br |
| Hazard Information | Back Directory | [Uses]
DSP-4 Hydrochloride is an adrenergic neuron blocking agent with inhibitory effects on the uptake of noradrenaline. | [Biological Activity]
Adrenergic neurotoxin. Displays neurotoxic effects on both peripheral and central noradrenergic neurons. | [Biochem/physiol Actions]
Adrenergic neurotoxin that induces acute and relatively selective degeneration of both central and peripheral noradrenergic nerve terminals. | [in vivo]
DSP-4 hydrochloride (i.p.; 50 mg/kg; single) destroys the LC neurons and fibers[1]. | Animal Model: | rats[1] | | Dosage: | 50 mg/kg | | Administration: | intraperitoneal , single | | Result: | Not visualized large projection neurons and the fibers of the LC. |
| [storage]
Desiccate at RT |
|
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
Rhawn Reagent
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http://www.rhawn.cn |
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