| Identification | Back Directory | [Name]
(4-hydroxy-4-oxobutyl)-trimethylazanium | [CAS]
407-64-7 | [Synonyms]
Actinine
Butyrobetaine
gamma-butyrobetaine
4-Trimethylaminiobutyrate
4-Trimethylammoniobutanoate
4-Trimethylammoniobutanoic acid
4-(Trimethylaminio)butyric acid anion
(4-hydroxy-4-oxobutyl)-trimethylazanium
3-Carboxylato-N,N,N-trimethyl-1-propanaminium | [EINECS(EC#)]
457-470-9 | [Molecular Formula]
C7H15NO2 | [MOL File]
407-64-7.mol | [Molecular Weight]
145.2 |
| Chemical Properties | Back Directory | [Boiling point ]
108.4-415.15℃ at 99.7-101.3kPa | [density ]
1.07 at 20℃ | [vapor pressure ]
0-3031.3Pa at 20-25℃ | [form ]
Liquid | [pka]
4.196±0.10(predicted) | [LogP]
-3.95 at 25℃ | [Surface tension]
70.2mN/m at 1g/L and 20℃ |
| Hazard Information | Back Directory | [Uses]
Actinine (γ-Butyrobetaine) is an amino acid betaine aminobutyric acid zwitterion. Actinine acts as both a human metabolite and a metabolite of E. coli[1]. | [Definition]
ChEBI: 4-(trimethylammonio)butanoate is an amino-acid betaine gamma-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups. It has a role as a human metabolite and an Escherichia coli metabolite. It is functionally related to a gamma-aminobutyrate and a gamma-aminobutyric acid zwitterion. It is a conjugate base of a 4-(trimethylammonio)butanoic acid. | [References]
[1] Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20(5):799-812. DOI:10.1016/j.cmet.2014.10.006 |
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