| Identification | Back Directory | [Name]
2-(2-Oxopropyl)-7-hydroxy-5-methyl-4H-1-benzopyran-4-one | [CAS]
40738-40-7 | [Synonyms]
Aloesone
2-Acetonyl-5-methyl-7-hydroxychromone
5-methyl-7-hydroxy-2-(2'-oxopropyl)chromone
2-acetonyl-7-hydroxy-5-methyl-chromen-4-one
7-Hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one
2-(2-Oxopropyl)-7-hydroxy-5-methyl-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-hydroxy-5-methyl-2-(2-oxopropyl)- | [Molecular Formula]
C13H12O4 | [MOL File]
40738-40-7.mol | [Molecular Weight]
232.23 |
| Hazard Information | Back Directory | [Uses]
Aloesone is a phenolic compound. Aloesone can inhibit the production of ROS, the release of NO, M1 polarization, and apoptosis in RAW264.7 cells stimulated by LPS (HY-D1056). Aloesone has anti-inflammatory and antioxidant activities[1][2]. | [Definition]
ChEBI: An aromatic heptaketide produced by rhubarb (Rheum palmatum, Polygonaceae). | [References]
[1] Reza Nazifi SM, et al. Antioxidant properties of Aloe vera components: a DFT theoretical evaluation. Free Radic Res. 2019 Aug;53(8):922-931. DOI:10.1080/10715762.2019.1648798
[2] Wang Y, et al. Multiple Beneficial Effects of Aloesone from Aloe vera on LPS-Induced RAW264.7 Cells, Including the Inhibition of Oxidative Stress, Inflammation, M1 Polarization, and Apoptosis. Molecules. 2023 Feb 8;28(4):1617. DOI:10.3390/molecules28041617 |
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