| Identification | Back Directory | [Name]
AKOS BB-3093 | [CAS]
41191-92-8 | [Synonyms]
AKOS BB-3093
Ethyl 3-Amino-p-toluate
3-aMino-4-Methyl-, ethyl ester
Ethyl3-Amino-4-methylbenzoate>
3-Amino-p-toluic Acid Ethyl Ester
3-AMINO-4-METHYLBENZOIC ACID ETHYL ESTER
Benzoic acid, 3-aMino-4-Methyl-, ethyl ester
ethyl 3-amino-4-methylbenzoate(SALTDATA: FREE) | [Molecular Formula]
C10H13NO2 | [MDL Number]
MFCD01926538 | [MOL File]
41191-92-8.mol | [Molecular Weight]
179.22 |
| Chemical Properties | Back Directory | [Melting point ]
48.6-50.1℃ | [Boiling point ]
105°C/0.2mmHg(lit.) | [density ]
1.103±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
3.35±0.10(Predicted) | [color ]
White to Almost white | [InChI]
InChI=1S/C10H13NO2/c1-3-13-10(12)8-5-4-7(2)9(11)6-8/h4-6H,3,11H2,1-2H3 | [InChIKey]
MCNBNDUVWQEKNZ-UHFFFAOYSA-N | [SMILES]
C(OCC)(=O)C1=CC=C(C)C(N)=C1 |
| Hazard Information | Back Directory | [Synthesis]
Dissolve 10 g of palladium on carbon (10%) and 140 g of ammonium formate in 400 ml of methanol, and then dissolve 136 g of ethyl 3-nitro-4-methylbenzoate (2) in 400 ml of methanol. Add the methanol solution of (2) dropwise to the reaction flask at room temperature. The reaction exotherms until the methanol boils. Continue the dropwise addition. After the dropwise addition, TLC detects the completion of the reaction and filters the palladium carbon. Concentrate the methanol, add 400ml of water, and filter to obtain 156g of white solid ethyl 3-amino-4-methylbenzoate (Ethyl 3-Amino-4-methylbenzoate) as a wet product, which can be used in the next step without drying.
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