| Identification | Back Directory | [Name]
Benzenesulfonamide, 4-cyclohexyl-N-(2-methylphenyl)- | [CAS]
413605-11-5 | [Synonyms]
LP471756
LP-471756
LP 471756
Benzenesulfonamide, 4-cyclohexyl-N-(2-methylphenyl)- | [Molecular Formula]
C19H23NO2S | [MOL File]
413605-11-5.mol | [Molecular Weight]
329.46 |
| Chemical Properties | Back Directory | [Boiling point ]
473.5±48.0 °C(Predicted) | [density ]
1.193±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
8.83±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
LP-471756 is antagonist of GPR139. | [Uses]
LP-471756 is a potent GPR139 antagonist with an IC50 value of 640 nM. LP-471756 inhibits LP-360924-stimulated cAMP production[1][2]. | [References]
[1] Vedel L, et al. Pharmacology and function of the orphan GPR139 G protein-coupled receptor. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6(Suppl 6):35-46. DOI:10.1111/bcpt.13263
[2] Hu LA, et al. Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139. J Biomol Screen. 2009 Aug;14(7):789-97. DOI:10.1177/1087057109335744 |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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