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413605-11-5

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413605-11-5 Structure

413605-11-5 Structure
IdentificationBack Directory
[Name]

Benzenesulfonamide, 4-cyclohexyl-N-(2-methylphenyl)-
[CAS]

413605-11-5
[Synonyms]

LP471756
LP-471756
LP 471756
Benzenesulfonamide, 4-cyclohexyl-N-(2-methylphenyl)-
[Molecular Formula]

C19H23NO2S
[MOL File]

413605-11-5.mol
[Molecular Weight]

329.46
Chemical PropertiesBack Directory
[Boiling point ]

473.5±48.0 °C(Predicted)
[density ]

1.193±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

8.83±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

LP-471756 is antagonist of GPR139.
[Uses]

LP-471756 is a potent GPR139 antagonist with an IC50 value of 640 nM. LP-471756 inhibits LP-360924-stimulated cAMP production[1][2].
[References]

[1] Vedel L, et al. Pharmacology and function of the orphan GPR139 G protein-coupled receptor. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6(Suppl 6):35-46. DOI:10.1111/bcpt.13263
[2] Hu LA, et al. Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139. J Biomol Screen. 2009 Aug;14(7):789-97. DOI:10.1177/1087057109335744
Spectrum DetailBack Directory
[Spectrum Detail]

Benzenesulfonamide, 4-cyclohexyl-N-(2-methylphenyl)-(413605-11-5)1HNMR
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