| Identification | Back Directory | [Name]
[2-(aminomethyl)phenyl]methanol | [CAS]
4152-92-5 | [Synonyms]
RARECHEM GT HW 0287
UKRORGSYN-BB BBV-182531
o-(Hydroxymethyl)benzylamine
[2-(aminomethyl)phenyl]methanol | [Molecular Formula]
C8H11NO | [MDL Number]
MFCD09035091 | [MOL File]
4152-92-5.mol | [Molecular Weight]
137.18 |
| Chemical Properties | Back Directory | [Boiling point ]
271℃ | [density ]
1.113 | [Fp ]
118℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
14.28±0.10(Predicted) | [Appearance]
Off-white to yellow Solid |
| Hazard Information | Back Directory | [Uses]
[2-(aminomethyl)phenyl]methanol can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
(4-Aminomethyl-phenyl)-methanol hydrochloride salt 4-Hydroxymethyl-benzonitrile (2.0 g, 15 mol) was reduced using Raney nickel (0. 5g) and hydrogen (50 psi) in MeOH: NH3 (100ml) for 20 hours. The reaction mixture was filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford (4-aminomethyl-phenyl)-methanol hydrochloride salt (2.01 g, 98percent) as a white solid of sufficient purity for use without further purification: MS (APCI+) : m/z 138.3 (M+H). |
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