| Identification | Back Directory | [Name]
ROSE BENGAL LACTONE | [CAS]
4159-77-7 | [Synonyms]
Solvent Red 141
ROSE BENGAL LACTONE
4’,5’,7’-tetraiodo-droxy-2
C.I.Solvent Red 141:C.I.45440:1
4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein
spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy
4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one
4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one | [EINECS(EC#)]
223-993-4 | [Molecular Formula]
C20H4Cl4I4O5 | [MDL Number]
MFCD00013321 | [MOL File]
4159-77-7.mol | [Molecular Weight]
973.67 |
| Chemical Properties | Back Directory | [Appearance]
Bluish-pink powder. Soluble in water.
| [Melting point ]
280 °C (dec.)(lit.)
| [storage temp. ]
room temp | [Boiling point ]
741.8±60.0 °C(Predicted) | [density ]
2.96±0.1 g/cm3(Predicted) | [form ]
powder | [pka]
7.03±0.20(Predicted) | [color ]
pink to red | [ε(extinction coefficient)]
≥10000 at 317-323nm
≥30000 at 516-522nm
≥95000 at 554-560nm | [λmax]
557 nm | [Uses]
Biological stain; colorant for inks, cellulosics,
foods, cosmetics, medicine (diagnostic aid).
| [EPA Substance Registry System]
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- (4159-77-7) |
| Hazard Information | Back Directory | [Chemical Properties]
Bluish-pink powder. Soluble in water.
| [Description]
Rose bengal lactone is a potent inhibitor of human metabolism that binds to the proteasome pathway and inhibits the polymerization of tubulin. It has been shown to bind with high affinity to microtubules and inhibit their assembly, which leads to cell death. Rose bengal lactone also binds with high affinity to potassium ion, which may contribute to its anti-cancer effects. This compound has also been found to be an effective inhibitor of goiters in rats by binding with aliphatic hydrocarbons such as cholesterol. | [Preparation]
will Resorcinol and 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione condensation, The resulting 4,5,6,7 – tetrachloro-fluorescein tetraiodide. | [Properties and Applications]
blue light red. Soluble in water for blue light yellow, no fluorescence, in concentrated sulfuric acid for brown, dilution after hot pink precipitation. Used in cosmetics coloring.
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Standard
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Light Fastness
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Heat-resistant(℃)
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water
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Sodium Carbonate(5%)
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Hydrochloric acid(5%)
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Melting point
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Stable
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ISO
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Poor
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Insoluble
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| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|