| Identification | Back Directory | [Name]
propan-2-yl 4-(3-methoxy-4-phenylmethoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate | [CAS]
418799-16-3 | [Synonyms]
propan-2-yl 4-(3-methoxy-4-phenylmethoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-[3-methoxy-4-(phenylmethoxy)phenyl]-6-methyl-2-oxo-, 1-methylethyl ester | [Molecular Formula]
C23H26N2O5 | [MOL File]
418799-16-3.mol | [Molecular Weight]
410.46 |
| Hazard Information | Back Directory | [Uses]
EGFR-IN-121 (compound 15) is a EGFR and VEGFR-2 dual inhibitor with IC50s of 84 and 3.5 nM, respectively[1]. | [References]
[1] Al-Wahaibi L H, et al. Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors[J]. ACS Omega, 2024. |
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