| Identification | Back Directory | [Name]
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- | [CAS]
42203-78-1 | [Synonyms]
Doi cpd hydrochloride
(+/-)-DOI hydrochloride
(+/-)-DOI hydrochloride >=98% (HPLC), solid
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride
(±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution
4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
(+/-)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution
Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, hydrochloride
BenzeneethanaMine,4-iodo-2,5-diMethoxy-a-Methyl-, hydrochloride (1:1) | [EINECS(EC#)]
636-989-6 | [Molecular Formula]
C11H16INO2.ClH | [MDL Number]
MFCD00055199 | [MOL File]
42203-78-1.mol | [Molecular Weight]
357.613 |
| Chemical Properties | Back Directory | [Fp ]
9℃ | [storage temp. ]
Store at RT | [solubility ]
H2O: soluble10mg/mL | [form ]
solid | [color ]
white to off-white | [Water Solubility ]
Soluble to 50 mM in water |
| Hazard Information | Back Directory | [Uses]
Hydrochloride (cas# 42203-78-1) is a useful research chemical.??DOI Hydrochloride is a 5-??HT2A??/2C agonist that stimulates hypothalamic neurons to increase the secretion of several hormones | [General Description]
A Certified Spiking Solution? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action. | [Biological Activity]
Brain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α . | [Biochem/physiol Actions]
(±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum. | [storage]
Store at RT |
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