| Identification | Back Directory | [Name]
PD 150,606 | [CAS]
426821-41-2 | [Synonyms]
3-(4-Iodophenyl)-2-mercapto-2-propenoic acid
2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto- | [Molecular Formula]
C9H7IO2S | [MDL Number]
MFCD00949076 | [MOL File]
426821-41-2.mol | [Molecular Weight]
306.12 |
| Hazard Information | Back Directory | [Definition]
ChEBI: (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid is an organoiodine compound that is acrylic acid in which the vinylic hydrogens at positions 2 and 3 are replaced by mercapto and 4-iodophenyl groups respectively (the Z geoisomer). It has a role as a calpain inhibitor and an apoptosis inhibitor. It is an organoiodine compound, a member of cinnamic acids and a thioenol. It is functionally related to a trans-cinnamic acid. | [Biological Activity]
Cell permeable: yes''Primary Target
Calpain-1''Product does not compete with ATP.''Reversible: no''Target Ki: 210 nM for calpain-1 and 370 nM for calpain-2 | [storage]
+4°C |
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| Company Name: |
Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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