Identification | Back Directory | [Name]
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one | [CAS]
4281-28-1 | [Synonyms]
Sudachitin 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy- | [Molecular Formula]
C18H16O8 | [MOL File]
4281-28-1.mol | [Molecular Weight]
360.31 |
Hazard Information | Back Directory | [Uses]
Sudachitin, a polymethoxyflavone that can be isolated from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. Sudachitin can activate the p38MAPK pathway and inhibit the ERK1/2 pathway in HaCaT cells[1]. | [Definition]
ChEBI: Sudachitin is an ether and a member of flavonoids. | [References]
[1] Keizo Yuasa, et al. Sudachitin, a polymethoxyflavone from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. Biosci Biotechnol Biochem. 2012;76(3):598-600. DOI:10.1271/bbb.110800 |
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