| Identification | Back Directory | [Name]
2,3-Dihydrobenzo[b]furan-5-ylamine | [CAS]
42933-43-7 | [Synonyms]
2,3-DIHYDROBENZOFURAN-5-AMINE
5-Amino-2,3-dihydrobenzofuran
5-Amino-2,3-dihydrobenzo[b]furan
2,3-Dihydrobenzo[b]furan-5-ylamine
5-AMino-2,3-dihydrobenzofuran, 97% 1GR
2,3-Dihydro-1-benzofuran-5-amine, 2,3-Dihydrobenzo[b]furan-5-amine | [Molecular Formula]
C8H9NO | [MDL Number]
MFCD03617969 | [MOL File]
42933-43-7.mol | [Molecular Weight]
135.16 |
| Chemical Properties | Back Directory | [Melting point ]
78-80℃ | [Boiling point ]
289.4±29.0 °C(Predicted) | [density ]
1.208±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Powder | [pka]
5.34±0.20(Predicted) | [color ]
White to light brown | [Water Solubility ]
Sparingly soluble in water.(0.26 g/L) (25°C), | [Sensitive ]
Air Sensitive | [CAS DataBase Reference]
42933-43-7 |
| Hazard Information | Back Directory | [Uses]
It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor. | [References]
[1] Journal of Medicinal Chemistry, 2010, vol. 53, # 18, p. 6681 - 6698
[2] Patent: EP2532665, 2012, A1. Location in patent: Page/Page column 21
[3] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 21, p. 6430 - 6446
[4] Journal of Medicinal Chemistry, 2014, vol. 57, # 13, p. 5579 - 5601
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 14, p. 4161 - 4172 |
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