ChemicalBook--->CAS DataBase List--->42935-17-1

42935-17-1

42935-17-1 Structure

42935-17-1 Structure
IdentificationBack Directory
[Name]

PROSTAGLANDIN H2
[CAS]

42935-17-1
[Synonyms]

PGH2
PGR2
GPR142
ENDOPEROXIDE H2
PROSTAGLANDIN R2
PROSTAGLANDIN H2
PGH2 (Prostaglandin H2)
[1-14C]Prostaglandin?H2
Prostaglandin?H2?(PGH2)
PROSTAGLANDIN H2 SOLUTION
G-protein coupled receptor PGR2
Probable G-protein coupled receptor 142
Endoperoxide H2, PGH2, Prostaglandin R2
ANTI-GPR142(N-TERMINAL) antibody produced in rabbit
Prostaglandin H2,Endoperoxide H2, PGH2, Prostaglandin R2
9ALPHA,11ALPHA-EPIDIOXY-15S-HYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
(5Z,13E,15S)-9α,11α-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 9,11-epidioxy-15-hydroxy-, (5Z,9α,11α,13E,15S)-
7-[5-(3-hydroxyoct-1-enyl)-2,3-dioxabicyclo[2.2.1]hept-6-yl]hept-5-enoic acid
(Z)-7-[(1S,2R,3S,4R)-3-[(E,3S)-3-hydroxyoct-1-enyl]-5,6-dioxabicyclo[2.2.1]hept-2-yl]hept-5-enoic acid
[EINECS(EC#)]

200-662-2
[Molecular Formula]

C20H32O5
[MDL Number]

MFCD00036972
[MOL File]

42935-17-1.mol
[Molecular Weight]

352.47
Chemical PropertiesBack Directory
[Boiling point ]

490.1±40.0 °C(Predicted)
[density ]

1.129±0.06 g/cm3(Predicted)
[Fp ]

-17 °C
[storage temp. ]

−70°C
[solubility ]

Ethanol: >100 mg/ml; PBS pH 7.2: >2 mg/ml
[form ]

acetone solution
[pka]

4.76±0.10(Predicted)
Safety DataBack Directory
[Hazard Codes ]

F,Xi
[Risk Statements ]

11-36-66-67
[Safety Statements ]

9-16-26
[RIDADR ]

UN 1090 3/PG 2
[WGK Germany ]

1
Hazard InformationBack Directory
[Description]

Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100 ng/ml.
[Uses]

PGH2 (Prostaglandin H2) is a thromboxane A2 precursor and a platelet aggregator of vascular smooth muscle contraction.
[Definition]

ChEBI: Prostaglandin H2 is an oxylipin, an olefinic compound, a secondary alcohol and a prostaglandins H. It has a role as a mouse metabolite. It is a conjugate acid of a prostaglandin H2(1-).
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