| Identification | Back Directory | [Name]
DESETHYL HYDROXY CHLOROQUINE | [CAS]
4298-15-1 | [Synonyms]
cletoquine
DESETHYL HYDROXY CHLOROQUINE
Desethyl Hydroxy Chloroquine DiHCl
Desethylhydroxychloroquine Dihydroc
Hydroxychloroquine Sulfate EP Impurity C
Hydroxychloroquine EP Impurity C (Phosphate)
2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol
2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol
Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-
Hydroxychloroquine Sulfate EP Impurity C (Desethyl Hydroxy Chloroquine)
Hydroxychloroquine Sulfate Impurity 3（Hydroxychloroquine Sulfate EP Impurity C）
Hydroxychloroquine?EP?Impurity?C/Desethyl?Hydroxychloroquine/Cletoquine/2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C16H22ClN3O | [MDL Number]
MFCD00868613 | [MOL File]
4298-15-1.mol | [Molecular Weight]
307.82 |
| Chemical Properties | Back Directory | [Melting point ]
112-115°C | [Boiling point ]
514.7±50.0 °C(Predicted) | [density ]
1.212±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.80±0.10(Predicted) | [color ]
Off-White to Yellow | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20) | [InChIKey]
XFICNUNWUREFDP-UHFFFAOYSA-N | [SMILES]
C(O)CNCCCC(NC1C2C(N=CC=1)=CC(Cl)=CC=2)C |
| Hazard Information | Back Directory | [Uses]
Cletoquine is a metabolite of Hydroxychloroquine (H916900), an antimalarial; antirheumatic; lupus erythematosus suppressant. | [in vivo]
Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine (Desethylhydroxychloroquine). The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed in the descending order of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5)[3]. | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
|