| Identification | Back Directory | [Name]
1-DODECYLIMIDAZOLE | [CAS]
4303-67-7 | [Synonyms]
C12IM
1-dodecliMidazole
1-laurylimidazole
n-laurylimidazole
N-DODECYLIMIDAZOLE
1-DODECYLIMIDAZOLE
1-dodecyl-imidazol
1-dodecyl-1h-imidazol
1-DODECYL-1H-IMIDAZOLE
1-Dodecylimidazole,95%
1-Dodecylimidazole,97%
1-DodecyliMidazole, GC 97% | [EINECS(EC#)]
224-314-4 | [Molecular Formula]
C15H28N2 | [MDL Number]
MFCD00278859 | [MOL File]
4303-67-7.mol | [Molecular Weight]
236.4 |
| Chemical Properties | Back Directory | [Appearance]
Clourless Liquid | [Melting point ]
69.5-70.5 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
146 °C (0.5 mmHg)
| [density ]
0.9624 (rough estimate) | [vapor pressure ]
0.009Pa at 20℃ | [refractive index ]
1.5312 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
7.08±0.10(Predicted) | [color ]
Clear yellow | [LogP]
3.56-5.5 at pH5-9 | [Surface tension]
45mN/m at 20mg/L and 20℃ | [EPA Substance Registry System]
1H-Imidazole, 1-dodecyl- (4303-67-7) |
| Hazard Information | Back Directory | [Chemical Properties]
Clourless Liquid | [Uses]
A N-alkylated derivative of imidazole as antibacterial agent. | [in vivo]
The hypocholesterolaemic activity of 1-dodecylimidazole results in part from the inhibition of cholesterol biosynthesis at the level of 2,3-oxidosqualene sterol cyclase[2].
1-dodecylimidazole (150 mg/kg body wt; by stomach tube; daily for 10 days) has lower serum cholesterol concentrations than control rats[2]. | Animal Model: | Male rats[2] | | Dosage: | 150 mg/kg body wt | | Administration: | By stomach tube; daily for 10 days | | Result: | Had significantly lower serum cholesterol concentrations than untreated animals.
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