| Identification | Back Directory | [Name]
HQ-415 | [CAS]
430462-93-4 | [Synonyms]
HQ-415
CS-2051
HQ 415,HQ415
7-[(3-ethoxy-4-methoxyphenyl)-[(4-methylpyridin-2-yl)amino]methyl]quinolin-8-ol
8-Quinolinol, 7-[(3-ethoxy-4-methoxyphenyl)[(4-methyl-2-pyridinyl)amino]methyl]- | [Molecular Formula]
C25H25N3O3 | [MDL Number]
MFCD02376369 | [MOL File]
430462-93-4.mol | [Molecular Weight]
415.48 |
| Chemical Properties | Back Directory | [Boiling point ]
614.9±55.0 °C(Predicted) | [density ]
1.246±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 5.6 mg/mL (13.48 mM) | [form ]
Solid | [pka]
4.13±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
HQ-415 is a biologically active metal chelator related to Clioquinol (HY-14603), with an EC50 of 15 μM. | [storage]
Store at -20°C | [References]
[1] Tardiff DF, et al. Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms. J Biol Chem. 2012 Feb 3;287(6):4107-4120. DOI:10.1074/jbc.M111.308668 |
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