ChemicalBook--->CAS DataBase List--->43188-86-9

43188-86-9

43188-86-9 Structure

43188-86-9 Structure
IdentificationBack Directory
[Name]

11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME
[CAS]

43188-86-9
[Synonyms]

CORTISOL 3-CMO
HYDROCORTISONE 3-CMO
Hydrocortisone Impurity 56
Cortisol 3-Carboxymethyloxime
CORTISOL 3-[O-CARBOXYMETHYL]OXIME
HYDROCORTISONE 3-(O-CARBOXYMETHYL)OXIME
Hydrocortisone 3-(O-Carboxymethyl)oxime (E/Z Mixture)
4-PREGNEN-11β, 17, 21-TRIOL-3, 20-DIONE 3-O-CARBOXYMETHYLOXIME
4-Pregnene-11β,17α,21-Triol-3,20-Dione 3-(O-Carboxymethyl)Oxime
4-Pregnene-11β,17α,21-triol-3,20-dione 3-(O-carboxymethyl)oxime
4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 3-O-CARBOXYMETHYLOXIME
11β,17α,21-trihydroxy-4-pregnene-3,20-dione 3-(o-carboxymethyl)oxime
4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME
11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME
Acetic acid, 2-[[[(11β)-11,17,21-trihydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy]-
Cortisol 3-(O-carboxymethyl)oxime, 4-Pregnene-11β,17α,21-triol-3,20-dione 3-(O-carboxymethyl)oxime, 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 3-(O-carboxymethyl)oxime
[Molecular Formula]

C23H33NO7
[MDL Number]

MFCD00056501
[MOL File]

43188-86-9.mol
[Molecular Weight]

435.51
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

chloroform: methanol (1:1): 20mg/mL, clear, colorless to light yellow
[form ]

powder
[biological source]

synthetic (organic)
[InChIKey]

WXAWNCDYPXVODT-ZAKIEOBNSA-N
[SMILES]

[H][C@@]12CCC3=CC(\CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO)=N\OCC(O)=O
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

1
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

Hydrocortisone 3-(O-carboxymethyl)oxime has been used in fecal steroid hormone processing and analysis.
[Uses]

Hydrocortisone 3-(O-Carboxymethyl)oxime is a model steroid that was coupled with bovine serum albumin (F-3-O-CMO-BSA) and used as immunogen to raise the antiserum in New Zealand white rabbits.It is derived from Hydrocortisone (H714615), which is a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
[Biochem/physiol Actions]

Hydrocortisone 3-(O-carboxymethyl)oxime is used as the analog of cortisol. It is used to modify the surface of an Au chip.
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