| Identification | Back Directory | [Name]
(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone | [CAS]
431996-53-1 | [Synonyms]
Filastatin
(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone
Methanone, (3-chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C18H18ClN3O3 | [MOL File]
431996-53-1.mol | [Molecular Weight]
359.81 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO: soluble15mg/mL, clear | [form ]
powder | [color ]
white to beige | [InChI]
1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3 | [InChIKey]
PNECWWUOUHGWQG-UHFFFAOYSA-N | [SMILES]
Clc1c(ccc(c1)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])C |
| Hazard Information | Back Directory | [Uses]
Filastatin is a novel inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis. | [Biological Activity]
Filastatin blocks the ability of Candida albicansand other Candida sp. to bind to polystyreneand human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1. | [storage]
Store at -20°C |
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Lynnchem
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