433224-56-7

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433224-56-7 Structure

Chemical Properties	Back Directory
[density ] 1.548±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 4.17±0.10(predicted)

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[Uses] GW701427A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 0.12 μM and 603 nM, respectively. GW701427A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].
[References] [1] Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8(3):e57888. DOI:10.1371/journal.pone.0057888

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