| Identification | Back Directory | [Name]
Defluoro Atorvastatin | [CAS]
433289-84-0 | [Synonyms]
Defluoro Atorvastatin
Atorvastatin EP IMP A
Desfluoro atorvastatin
Defluoro atorvastatin calcium salt
Atorvastatin Calcium Hydrate Impurity A
Atorvastatin Impurity 26（Atorvastatin EP Impurity A）
Atorvastatin EP Impurity A Calcium Salt (Defluoro Atorvastatin Calcium Salt)
(3R,5R)-7-[2,3-diphenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
(bR,dR)-b,d-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
1H-Pyrrole-1-heptanoicacid, b,d-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-,(bR,dR)-
1H-Pyrrole-1-heptanoic acid, β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-, (βR,δR)-
(betaR,deltaR)-beta,delta-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid | [Molecular Formula]
C33H36N2O5 | [MDL Number]
MFCD09832913 | [MOL File]
433289-84-0.mol | [Molecular Weight]
540.65 |
| Chemical Properties | Back Directory | [Melting point ]
>193°C (dec.) | [Boiling point ]
723.7±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly, Sonicated), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
4.29±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Desfluoroatorvastatin is an impurity of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. | [Definition]
ChEBI: Defluoroatorvastatin is a member of pyrroles. |
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