| Identification | Back Directory | [Name]
LasMiditan | [CAS]
439239-90-4 | [Synonyms]
CS-2381
COL 144
LY573144
LasMiditan
Lasmiditant
COL-144; LY573144
LasMiditan (COL-144
COL-144; LY-573144;COL144; LY 573144
2,4-difluoro-N-(6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl)benzamide
2,4,6-trifluoro-N-(6-(1-Methylpiperidine-4-carbonyl)pyridin-2-yl)benzaMide
2,4,6-Trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]benzamide
Benzamide, 2,4,6-trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]- | [Molecular Formula]
C19H18F3N3O2 | [MDL Number]
MFCD18633238 | [MOL File]
439239-90-4.mol | [Molecular Weight]
377.36 |
| Chemical Properties | Back Directory | [Melting point ]
255℃ | [Boiling point ]
433.3±45.0 °C(Predicted) | [density ]
1.351 | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
9.91±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Lasmiditan (Item No. 28369) is an analytical reference standard categorized as an agonist of the serotonin (5-HT) receptor subtype 5-HT1F.1 Formulations containing lasmiditan have been used in the treatment of migraine headache. Lasmiditan has low abuse potential.2 Lasmiditan is regulated as a Schedule V compound in the United States. This product is intended for research and forensic applications. | [Uses]
Lasmiditan is used in diagnosing, treating and/or preventing periodontal disease and/or tooth loss. | [Synthesis]
synthesis route of LasMiditan
 | [References]
[1] DAVID L NELSON. Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.[J]. ACS Applied Materials & Interfaces, 2010: 1159-1169. DOI: 10.1177/0333102410370873
[2] DARREN WILBRAHAM MBBS, PHD. Abuse Potential of Lasmiditan: A Phase 1 Randomized, Placebo- and Alprazolam-Controlled Crossover Study[J]. The Journal of Clinical Pharmacology, 2019, 60 4: 495-504. DOI: 10.1002/jcph.1543 |
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| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
|