| Identification | Back Directory | [Name]
3'-Deoxy-3'-fluoro-6-azauridine | [CAS]
439579-23-4 | [Synonyms]
3'-Deoxy-3'-fluoro-6-azauridine
1,2,4-Triazine-3,5(2H,4H)-dione, 2-(3-deoxy-3-fluoro-β-D-ribofuranosyl)- | [Molecular Formula]
C8H10FN3O5 | [MDL Number]
MFCD30570204 | [MOL File]
439579-23-4.mol | [Molecular Weight]
247.18 |
| Chemical Properties | Back Directory | [Melting point ]
165 °C(Solv: dichloromethane (75-09-2); methanol (67-56-1)) | [density ]
2.00±0.1 g/cm3(Predicted) | [pka]
7.72±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
3’-Deoxy-3’-fluoro-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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