| Identification | Back Directory | [Name]
4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL | [CAS]
439814-87-6 | [Synonyms]
-2-fluorobenzene
4-Bromo-1-(dimethoxymethyl)
4-Bromo-1-(dimethoxymethyl)-2-fluorobenzene
4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL
Benzene, 4-bromo-1-(dimethoxymethyl)-2-fluoro- | [Molecular Formula]
C9H10BrFO2 | [MDL Number]
MFCD07780632 | [MOL File]
439814-87-6.mol | [Molecular Weight]
249.08 |
| Hazard Information | Back Directory | [Synthesis]
Step 1: Synthesis of 4-bromo-1-(dimethoxymethyl)-2-fluorobenzene
4-Bromo-2-fluorobenzaldehyde (5 g, 24.6 mmol) was dissolved in 2 M methanol hydrochloric acid solution (100 mL) and stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction solution was concentrated and dried under reduced pressure to afford the title compound 4-bromo-1-(dimethoxymethyl)-2-fluorobenzene (6.1 g, 99% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.52-7.39 (m, 1H), 7.33-7.27 (m, 1H), 7.27-7.20 (m, 1H), 5.54 (s, 1H), 3.36 (s, 6H). | [References]
[1] Patent: WO2013/92941, 2013, A1. Location in patent: Page/Page column 39
[2] Patent: US2006/58361, 2006, A1. Location in patent: Page/Page column 32 |
|
|