ChemicalBook--->CAS DataBase List--->443103-97-7

443103-97-7

Request For Quotation
443103-97-7 Structure

443103-97-7 Structure
IdentificationBack Directory
[Name]

CPI-444
[CAS]

443103-97-7
[Synonyms]

A2AR antagonist 1
A2A receptor antagonist 1
1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 1-[(2-fluorophenyl)methyl]-4-(2-furanyl)-
CPI444,CPI 444,Adenosine Receptor,disease,Parkinson,Inhibitor,CPI-444,hypolocomotion,inhibit,model,P1 receptor
[Molecular Formula]

C16H12FN5O
[MDL Number]

MFCD31544344
[MOL File]

443103-97-7.mol
[Molecular Weight]

309.3
Chemical PropertiesBack Directory
[Boiling point ]

570.6±60.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 62 mg/mL (200.45 mM)
[form ]

Solid
[pka]

3.17±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively[1].
[storage]

Store at -20°C
[References]

[1] Gillespie RJ, et al. Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines. Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9. DOI:10.1016/j.bmcl.2008.03.072
Spectrum DetailBack Directory
[Spectrum Detail]

CPI-444(443103-97-7)1HNMR
443103-97-7 suppliers list
Company Name: ShangHai KenEn Chemical Technology Co., Ltd.  
Telephone: 13120367189;18621755571
Website: www.chemicalbook.com/ShowSupplierProductsList16352/0_EN.htm
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Telephone: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 18916372613
Website: www.shyuanye.com
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Telephone: 17801761073 18101056239
Website: http://www.solarbio.com
Company Name: Yujinpharma(Tianjin) Technology Co.,Ltd.  
Telephone: 13370351217 kungfu1217@1
Website: http://www.yujinpharma.com
Company Name: Guangzhou Tomums Life Science Co., Ltd.  
Telephone: 020-31155029 18902330969
Website: http://www.tomums.cn/
Company Name: Finetech Industry Limited  
Telephone: +86-27-8746-5837 +86-18627785180
Website: https://www.finetechnology-ind.com/
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Telephone: 18818260767
Website: http://www.chemegen.com
Company Name: CONIER CHEM AND PHARMA LIMITED  
Telephone:
Website: http://www.conier.com/
Company Name: Shanghai hongqu biomedical technology co. LTD  
Telephone: 88888888888
Website: www.chemicalbook.com/ShowSupplierProductsList873228/0_EN.htm
Company Name: Birdo (Shanghai) Medical Technology Co., Ltd.  
Telephone: 021-58099077-8041 18601625411
Website: https://product.birdotech.com/
Company Name: Taizhou Nanfeng Pharmaceutical Research Institute  
Telephone: nanfengpharma@126.co 18616377689
Website: www.chemicalbook.com/showsupplierproductslist1580880/0.htm
Company Name: Zhengzhou Alpha Chemical Co. LTD  
Telephone: 0371-53732842 13383863444
Website: www.chemicalbook.com/supplier/23629674/
Company Name: Chunchuang (Wuhan) Technology Co., Ltd  
Telephone: 15727060112
Website: www.chemicalbook.com/showsupplierproductslist1427518/0_en.htm
Company Name: Energy Chemical  
Telephone: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Telephone: 15865264761
Website: www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Telephone: 010-60605840
Website: http://www.jm-bio.com/
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Tags:443103-97-7 Related Product Information
124431-80-7 155270-99-8 1321514-06-0 2620-62-4 1092351-10-4