| Identification | Back Directory | [Name]
BC 11 hydrobroMide | [CAS]
443776-49-6 | [Synonyms]
BC 11 hydrobroMide
Carbamimidothioic acid (4-boronophenyl)methyl ester hydrobromide | [Molecular Formula]
C8H12BBrN2O2S | [MDL Number]
MFCD20926359 | [MOL File]
443776-49-6.mol | [Molecular Weight]
290.97 |
| Chemical Properties | Back Directory | [Melting point ]
177 - 182°C | [storage temp. ]
Hygroscopic, Refrigerator, Under inert atmosphere | [solubility ]
Aqueous Base (Slightly), DMSO (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
H2O: 2mg/mL, clear (warmed) | [Stability:]
Hygroscopic | [InChI]
1S/C8H11BN2O2S.BrH/c10-8(11)14-5-6-1-3-7(4-2-6)9(12)13;/h1-4,12-13H,5H2,(H3,10,11);1H | [InChIKey]
PAFZAMOVHIRQOD-UHFFFAOYSA-N | [SMILES]
B(O)(O)c1ccc(cc1)CS\C(=N/[H])\N.Br |
| Hazard Information | Back Directory | [Uses]
BC 11 Hydrobromide, is a selective urokinase (uPA) inhibitor. It inhibits clot lysis without haveing any effect on clot formation. It has also shown to be able to decrease viability of MDA-MB231 breast cancer cells in vitro. | [Biological Activity]
BC-11 is a potent and selective inhibitor of urokinase (urokinase-plasminogen activatoruPA). BC-11 inhibits clot lysis with no effect on clot formation. BC-11 exhibits anti-fibrotic activity and improves wound healing and scar quality after topical administration in mice. | [storage]
Store at -20°C |
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