Identification | Back Directory | [Name]
3'-Deoxy-3'--C-methylguanosine | [CAS]
444020-69-3 | [Synonyms]
3'-Deoxy-3'-methylguanosine 3'-Deoxy-3'--C-methylguanosine Guanosine, 3'-deoxy-3'-methyl- 3’-Deoxy-3’-α-C-methylguanosine 3’-Deoxy-3’-a-C-methylguanosine 3'-Deoxy-3'-alpha-C-methylguanosine | [Molecular Formula]
C11H15N5O4 | [MDL Number]
MFCD30570266 | [MOL File]
444020-69-3.mol | [Molecular Weight]
281.27 |
Hazard Information | Back Directory | [Uses]
3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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