| Identification | Back Directory | [Name]
2-[(5-{[2-(4-chloroanilino)-2-oxoethyl]sulfanyl}-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-chlorophenyl)acetamide | [CAS]
444792-16-9 | [Synonyms]
Cy-FBP/SBPase-IN-1
2,2'-(1,3,4-thiadiazole-2,5-diyldisulfanediyl)bis[N-(4-chlorophenyl)acetamide]
Acetamide, 2,2'-[1,3,4-thiadiazole-2,5-diylbis(thio)]bis[N-(4-chlorophenyl)- (9CI)
2-[(5-{[2-(4-chloroanilino)-2-oxoethyl]sulfanyl}-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-chlorophenyl)acetamide | [Molecular Formula]
C18H14Cl2N4O2S3 | [MDL Number]
MFCD01886058 | [MOL File]
444792-16-9.mol | [Molecular Weight]
485.43 |
| Hazard Information | Back Directory | [Uses]
Cy-FBP/SBPase-IN-1 (compound S5) is a Cy-FBP/SBPase inhibitor, which is an important regulatory enzyme in cyanobacterial photosynthesis. Thus Cy-FBP/SBPase-IN-1 inhibits Calvin cycle and photosystem, and decreases photosynthetic efficiency in cyanobacterial photosynthesis. Cy-FBP/SBPase-IN-1 potently inhibits the growth of cyanobacteria, as well as Synechocystis sp.PCC6803. Cy-FBP/SBPase-IN-1 shows safety profile in human-derived cells and zebrafish models[1]. | [References]
[1] Zuo L, et al. Design, Synthesis, and Bioassay for the Thiadiazole-Bridged Thioacetamide Compound as Cy-FBP/SBPase Inhibitors Based on Catalytic Mechanism Virtual Screening. J Agric Food Chem. 2023 Aug 9;71(31):11834-11846. DOI:10.1021/acs.jafc.3c01913 |
|
| Company Name: |
Specs
|
| Tel: |
+31 15 251 8111 |
| Website: |
www.specs.net |
|