| Identification | Back Directory | [Name]
N-Desethyl Vardenafil | [CAS]
448184-46-1 | [Synonyms]
Desethyl vardenafil
Vardenafil N-Desethyl Imp
N-Desethyl-N-propylvardenafil
Vardenafil Related Compound E
N-Desethyl Vardenafil Impurity
Vardenafil N-Desethyl Impurity
Vardena hydrochloride impurity E
Vardenafil USP Related Compound E
Vardenafil Impurity 4(Vardenafil N-Desethyl Impurity)
2-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
2-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one
2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one
Imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 2-[2-ethoxy-5-(1-piperazinylsulfonyl)phenyl]-5-methyl-7-propyl-
1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazine
N-Desethyl VardenafilQ: What is
N-Desethyl Vardenafil Q: What is the CAS Number of
N-Desethyl Vardenafil Q: What is the storage condition of
N-Desethyl Vardenafil Q: What are the applications of
N-Desethyl Vardenafil | [Molecular Formula]
C21H28N6O4S | [MOL File]
448184-46-1.mol | [Molecular Weight]
460.55 |
| Chemical Properties | Back Directory | [Boiling point ]
699.8±65.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
DMF: 30mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL | [form ]
A crystalline solid | [pka]
7.73±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5. | [Chemical Properties]
White to Off-White Solid | [Uses]
A metabolite of Vardenafil, a phosphodiesterase 5 inhibitor | [Uses]
N-Desethyl Vardenafil is a metabolite of Vardenafil, a phosphodiesterase 5 inhibitor. | [storage]
Store at -20°C | [References]
[1] HEI-YOUNG KU. The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil.[J]. Drug Metabolism and Disposition, 2008, 36 6: 986-990. DOI: 10.1124/dmd.107.020099 |
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J & K SCIENTIFIC LTD.
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https://www.jkchemical.com |
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TOSUN PHARM
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www.toref.cn/ |
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