| Identification | Back Directory | [Name]
1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride | [CAS]
455311-98-5 | [Synonyms]
BEPP monohydrochloride
1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride | [Molecular Formula]
C23H24ClN3O2 | [MDL Number]
MFCD00964481 | [MOL File]
455311-98-5.mol | [Molecular Weight]
409.909 |
| Hazard Information | Back Directory | [Uses]
BEPP Monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator. Apoptosis. | [Biological Activity]
BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinaseinducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities)modulating activities of eIF2αNF-KBATF-3and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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