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457643-60-6

457643-60-6 Structure

457643-60-6 Structure
IdentificationBack Directory
[Name]

Rinvanil >=98% (HPLC)
[CAS]

457643-60-6
[Synonyms]

Rinvanil >=98% (HPLC)
9-Octadecenamide, 12-hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-, (9Z,12R)-
[Molecular Formula]

C26H43NO4
[MDL Number]

MFCD30146418
[MOL File]

457643-60-6.mol
[Molecular Weight]

433.62
Chemical PropertiesBack Directory
[Boiling point ]

633.0±55.0 °C(Predicted)
[density ]

1.025±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[form ]

oil
[pka]

9.76±0.20(Predicted)
[color ]

colorless to yellow
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

10 - Combustible liquids
Hazard InformationBack Directory
[Biological Activity]

Rinvanil is a Capsaicin analogue th at potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLaCaSKiViBo) and leukemia (P388J774WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes.''TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brainit regulates neuronal functionmotor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1.
457643-60-6 suppliers list
Company Name: Energy Chemical  
Telephone: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
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