462128-39-8

73183-34-3

474918-32-6

462128-39-8

The general procedure for the synthesis of 2-(9,9-diphenyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane from biphenylpinacol ester and 2-bromo-9,9-diphenylfluorene was carried out in the following manner: in a single-necked round-bottomed flask, 2-bromo-9,9-diphenyl-9H-fluorene (40 g, 100.67 mmol), biphenylpinacol ester (51.1 g, 201.34 mmol), PdCl2(dppf) (2.2 g, 3.02 mmol), KOAc (29.6 g, 302.01 mmol) and DMF (400 ml) were mixed and the reaction was carried out at reflux. Upon completion of the reaction, the mixture was extracted with dichloromethane and the organic phase was dried with anhydrous MgSO4, followed by removal of the solvent DMF under reduced pressure by rotary evaporator.The crude product was purified by column chromatography (silica gel as stationary phase, eluent hexane and dichloromethane in a 1:1 ratio, v/v/v/v) to afford the white solid product 2-(9,9-diphenyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl- 1,3,2-dioxaborolane (41 g, 91% yield).