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46492-08-4

46492-08-4 Structure

46492-08-4 Structure
IdentificationBack Directory
[Name]

BENZ[G]ISOQUINOLINE-5,10-DIONE
[CAS]

46492-08-4
[Synonyms]

Bgid
Biquidone
Nsc 338695
2-Azaanthraquinone
3,4-Phthaloylpyridine
β-Anthrapyridinequinone
2-aza-9,10-anthraquinone
BENZ[G]ISOQUINOLINE-5,10-DIONE
benzo(g)isoquinoline-5,10-dione
Benz[g]isoquinoline-5,10-dione 99%
5,10-Dihydrobenzo[g]isoquinoline-5,10-dione
Benz[g]isoquinoline-5,10-dione
[Molecular Formula]

C13H7NO2
[MDL Number]

MFCD00010399
[MOL File]

46492-08-4.mol
[Molecular Weight]

209.2
Chemical PropertiesBack Directory
[Melting point ]

178-180 °C(lit.)
[Boiling point ]

407℃
[density ]

1.373
[Fp ]

202℃
[pka]

1.10±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Benz[g]isoquinoline-5,10-dione, an active component isolated from the ethanolic extract of the aerial parts of Mitracarpus scaber, demonstrates notable in vitro inhibitory activity against AIDS-related pathogens, along with significant antibacterial and antifungal properties, as evidenced by the agar well-diffusion assay.
[General Description]

Benz[g]isoquinoline-5,10-dione has been isolated as an active component from the ethanolic extract of the aerial parts of Mitracarpus scaber. It exhibits significant in vitro inhibitory activity against the AIDS-related pathogens. The in vitro antibacterial and anti-fungal activity of benz[g]isoquinoline-5,10-dione has been investigated using the agar well-diffusion assay.
[References]

[1] Quantitative determination of lysophosphatidic acid by LC/ESI/MS/MS employing a reversed phase HPLC column
[2] Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
[3] Lysophosphatidic acid triggers apoptosis in HeLa cells through the upregulation of tumor necrosis factor receptor superfamily member 21
[4] Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Spectrum DetailBack Directory
[Spectrum Detail]

BENZ[G]ISOQUINOLINE-5,10-DIONE(46492-08-4)1HNMR
BENZ[G]ISOQUINOLINE-5,10-DIONE(46492-08-4)Raman
BENZ[G]ISOQUINOLINE-5,10-DIONE(46492-08-4)IR
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