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465-02-1

465-02-1 Structure

465-02-1 Structure
IdentificationBack Directory
[Name]

GERMANICOL
[CAS]

465-02-1
[Synonyms]

GERMANICOL
5α-Olean-18-en-3β-ol
Olean-18-en-3-ol, (3β)-
[Molecular Formula]

C30H50O
[MOL File]

465-02-1.mol
[Molecular Weight]

426.72
Chemical PropertiesBack Directory
[Melting point ]

180-181 °C
[Boiling point ]

490.7±44.0 °C(Predicted)
[density ]

1.01±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

15.19±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Germanicol is a selective antineoplastic agent against human colon cancer cell lines HCT-116 and HT29 . Germanicol induces apoptosis via chromatin condensation and DNA damage[1].
[Definition]

ChEBI: A pentacyclic triterpenoid that is oleanane substituted by a hydroxy group at the 3beta-position and with a double bond between positioins 18 and 19.
[References]

[1] Dong L C. Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibition of cell migration[J]. 2016.
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