| Identification | Back Directory | [Name]
ethylene dimethanesulfonate | [CAS]
4672-49-5 | [Synonyms]
Eds
Dmse
Ethylene bis(me
ETHYLENEDIMESYLATE
1,2-Bis(mesyloxy)ethane
ETHANEDIMETHANESULFONATE
Ethylene glycol dimesylate
ethylene dimethanesulfonate
ETHYLENEDIMETHANESULPHONATE
Ethylene bis(methanesulfonate)
Dimethylene dimethanesulfonate
1,2-Bis(methanesulfonyloxy)ethane
1,2-Ethanediyl dimethanesulfonate
ETHYLENEGLYCOL,DIMETHANESULPHONATE
1,2-Ethanediol di(methanesulfonate)
Ethylene glycol di(methanesulfonate)
1,2-Ethanediol, 1,2-dimethanesulfonate
Bis(methanesulfonic acid)ethylene ester
2-methylsulfonyloxyethyl methanesulfonate | [Molecular Formula]
C4H10O6S2 | [MDL Number]
MFCD00025060 | [MOL File]
4672-49-5.mol | [Molecular Weight]
218.25 |
| Chemical Properties | Back Directory | [Melting point ]
35-36 °C | [Boiling point ]
328.93°C (rough estimate) | [density ]
1.400 (estimate) | [refractive index ]
1.5630 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Sparingly, Heated), Methanol (Very Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs[1]. | [Biological Activity]
Ethylene dimethanesulfonate is a mild alkylated ethylene glycol nonvolatile methanesulfonate diester. It has a selective pro-apoptotic effect on LC. | [in vivo]
Ethylene dimethanesulfonate (subcutaneous injection; 75 mg/kg; 7 days) disrupts epididymal function and leads to sperm granuloma formation in rat. | [storage]
Store at -20°C | [References]
[1] Dutta D, et al. Ethylene dimethane sulfonate (EDS) ablation of Leydig cells in adult rat depletes testosterone resulting in epididymal sperm granuloma: Testosterone replacement prevents granuloma formation. Reprod Biol. 2019 Mar;19(1):89-99. DOI:10.1016/j.repbio.2018.11.005 |
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