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469-36-3

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469-36-3 Structure

469-36-3 Structure
IdentificationBack Directory
[Name]

ORYZANOL
[CAS]

469-36-3
[Synonyms]

ORYZANOL
Oryzanol C
[Molecular Formula]

C41H60O4
[MDL Number]

MFCD03457842
[MOL File]

469-36-3.mol
[Molecular Weight]

616.921
Chemical PropertiesBack Directory
[Melting point ]

193-194 °C
[Boiling point ]

668.4±40.0 °C(Predicted)
[density ]

1.09±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[form ]

Solid
[pka]

8?+-.0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1].
[IC 50]

Akt1: 33.3 μM (EC50)
[References]

[1] Heon Woong Kim, et al. 24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells. Biochem Biophys Res Commun. 2015 Dec 25;468(4):574-9. DOI:10.1016/j.bbrc.2015.10.147
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