| Identification | Back Directory | [Name]
VERATROSINE | [CAS]
475-00-3 | [Synonyms]
VERATROSINE
Veratramine 3-glucoside
Veratramine 3-O-glucoside
3-O-beta-D-Glucopyranosylveratramine
14,15,16,17-Tetradehydro-23β-hydroxyveratraman-3β-yl β-D-glucopyranoside
β-D-Glucopyranoside, (3β,23β)-14,15,16,17-tetradehydro-23-hydroxyveratraman-3-yl | [Molecular Formula]
C33H49NO7 | [MOL File]
475-00-3.mol | [Molecular Weight]
571.74 |
| Chemical Properties | Back Directory | [Melting point ]
237.8-239.7℃ (methanol ) | [Boiling point ]
740.7±60.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
12.91±0.70(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Description]
This glucoalkaloid occurs with pseudojervine in Veratrum viride. The melting
point given above is that obtained in an open tube; in an evacuated tube it is
276-8°C. The base is laevorotatory having [α]25D - 53.0° (EtOH-CHCI3) and on
hydrolysis with boiling, dilute HCl it furnishes P+)-glucose and Veratramine
(q.v.). | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Veratrum nigrum L. | [Uses]
Veratrosine is a steroidal alkaloid obtained from Veratrum dahuricum which has displayed antitumor and anti-platelet activity, inhibiting the hedgehog pathway in NIH?/3T3 cells | [References]
Jacobs, Craig.,]. Biol. Chem., 155,565 (1944) |
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