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477-27-0

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477-27-0 Structure

477-27-0 Structure
IdentificationBack Directory
[Name]

colchiceine
[CAS]

477-27-0
[Synonyms]

NSC 3341
NSC 33411
colchiceine
O10-Demethylcolchicine
Colchicine EP Impurity F
(S)-7-Acetylamino-10-hydroxy-1,2,3-trimethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one
N-[(7S)-5,6,7,9-Tetrahydro-10-hydroxy-1,2,3,-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
[EINECS(EC#)]

207-512-5
[Molecular Formula]

C21H23NO6
[MOL File]

477-27-0.mol
[Molecular Weight]

385.414
Chemical PropertiesBack Directory
[Appearance]

Off-White to Pale Yellow Solid
[Melting point ]

172-1740C
[alpha ]

D25 -255.1° (c = 1 in chloroform)
[Boiling point ]

511.86°C (rough estimate)
[density ]

1.2400
[refractive index ]

1.5614 (estimate)
[storage temp. ]

Refrigerator
[pka]

7.59±0.40(Predicted)
Hazard InformationBack Directory
[Chemical Properties]

Off- White to Pale Yellow Solid
[Uses]

A metabolite of Colchicine
[Definition]

ChEBI: Colchiceine is a cyclic ketone.
Safety DataBack Directory
[Toxicity]

LD50 intraperitoneal in mouse: 84mg/kg
Spectrum DetailBack Directory
[Spectrum Detail]

colchiceine(477-27-0)1HNMR
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