| Identification | Back Directory | [Name]
CARDIN | [CAS]
477-32-7 | [Synonyms]
Selva
CARDIN
cardine
carduben
VISNADIN
visnadine
carduben-s
CARDIN USP/EP/BP
Visnadine >=95% (LC/MS-ELSD)
2h,8h-benzo(1,2-b:3,4-b’)dipyran-2-one-acetate
3-(alpha-methylbutyryloxy)-4-acetoxy-3,4-dihydroseseline
(alpha-methylbutyryloxy)-3’-acetoxy-4’-dihydro-3’,4’-seselin
2-methyl-,9-esterwith9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-butyricaci
(9R)-9,10-Dihydro-9α,10α-dihydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one 10-acetate 9-[(R)-α-methylbutyrate]
(R)-2-Methylbutyric acid (9R,10α)-10-acetyloxy-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester
Butanoic acid,2-methyl-,(9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-ylester, (2R)- | [EINECS(EC#)]
207-515-1 | [Molecular Formula]
C21H24O7 | [MDL Number]
MFCD00075897 | [MOL File]
477-32-7.mol | [Molecular Weight]
388.41 |
| Questions And Answer | Back Directory | [Preparation]
Crude CARDIN was thoroughly mixed with petroleum ether at a rate of 100 cc ether per kilogram of pectin. This produced a homogeneous pulp, which was then allowed to stand at approximately 150°C for 24 hours and subsequently filtered through a Buchner funnel to recover purified CARDIN in a yield of 85-90%. |
| Chemical Properties | Back Directory | [Melting point ]
85-88° | [alpha ]
D20 +9.2° (alc); D30 +42.5° (c = 2 in dioxane) | [Boiling point ]
434.13°C (rough estimate) | [density ]
1.2086 (rough estimate) | [refractive index ]
1.5300 (estimate) | [storage temp. ]
?20°C | [form ]
solid | [Cosmetics Ingredients Functions]
SKIN CONDITIONING | [CAS DataBase Reference]
477-32-7 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-50 | [Safety Statements ]
61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3 | [Toxicity]
LD50 in mice (mg/kg): 2240 orally; >370 s.c. (Erbring) |
| Hazard Information | Back Directory | [Originator]
Vibeline ,Bellon ,France,1960 | [Uses]
Visnadine is used as a coumarin scaffold for anti-inflammatory drug development, melanin biosynthetic inhibitory activity, anticellulite efficacy in female patient with cellulite blemish affected by fat accumulation or new anticellulite treatment. | [Definition]
ChEBI: Visnadin is a member of coumarins. | [Manufacturing Process]
Ammi visnaga is a plant of the Umbelliferae family, which has been known and
used for its therapeutic properties by the peoples of the Mediterranean basin
since time immemorial.
Visnadine may be extracted from the umbels of Ammi visnaga by an organic
solvent having a boiling point less than 110°C. The resulting solution is
concentrated first by heating in a water bath and then is allowed to stand
some time at a temperature of about 20°C and if necessary is treated for
separation of gummy constituents therefrom, after which the solution is
concentrated under reduced pressure. Finally, the crude product is crystallized
and separated by retaining it on a filter.
This crude product may then, according to the process, be purified by mixing
it with petroleum ether and allowing it to stand at ordinary temperature, then
filtering it to obtain the pure visnadine. | [Therapeutic Function]
Coronary vasodilator, Antiarrhythmic |
|
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-29-81139210 17389186172 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-219/ |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|