| Identification | Back Directory | [Name]
Podophyllotoxone | [CAS]
477-49-6 | [Synonyms]
Podophyllotoxone
Podophyllotoxinone
(-)-podophyllotoxon
(-)-podophyllotoxon
(5R)-5aα,8aβ-Dihydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9(5H,8H)-dione
(5R)-5,5aα,8,8aβ-Tetrahydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9-dione
(5aR)-5aα,6,8aβ,9-Tetrahydro-9α-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione
(5R)-5,8,8aβ,9-Tetrahydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6(5aαH),9-dione
(5R)-5β-(3,4,5-Trimethoxyphenyl)-5,8,8aβ,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9(5aαH)-dione
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione, 5a,6,8a,9-tetrahydro-9-(3,4,5-trimethoxyphenyl)-, (5aR,8aR,9R)- | [Molecular Formula]
C22H20O8 | [MDL Number]
MFCD02183443 | [MOL File]
477-49-6.mol | [Molecular Weight]
412.39 |
| Chemical Properties | Back Directory | [Melting point ]
191.73℃ | [Boiling point ]
602.3±55.0 °C(Predicted) | [density ]
1.365±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
4°C, away from moisture and light | [solubility ]
DMSO : 100 mg/mL (242.49 mM; Need ultrasonic) | [form ]
Solid | [color ]
White to off-white | [InChI]
InChI=1S/C22H20O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-19H,8-9H2,1-3H3/t13-,18+,19-/m0/s1 | [InChIKey]
ISCQYPPCSYRZOT-BKTGTZMESA-N | [SMILES]
O1C2=CC3=C(C=C2OC1)C(=O)[C@@]1([H])COC(=O)[C@]1([H])[C@@H]3C1=CC(OC)=C(OC)C(OC)=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
It is a white crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It comes from the rhizomes of Sinopodophyllum hexandrum (Royle) Ying (the highest content is found in Anhui) and Dysosma versipellis (Hance) M. Cheng ex Ying (the highest content is found in Anhui). | [Uses]
Podophyllotoxone is a naturally occurring flavonoid that shown significant cell apoptosis and antiproliferative affect against human PC-3 and Bcap-37 cancer cell lines | [Definition]
ChEBI: Podophyllotoxone is a lactone and a lignan. | [storage]
4°C, away from moisture and light |
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