| Identification | Back Directory | [Name]
11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one | [CAS]
477-82-7 | [Synonyms]
Evoxanthine
11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one
1,3-Dioxolo[4,5-b]acridin-10(5H)-one, 11-methoxy-5-methyl- | [Molecular Formula]
C16H13NO4 | [MDL Number]
MFCD29918700 | [MOL File]
477-82-7.mol | [Molecular Weight]
283.28 |
| Hazard Information | Back Directory | [Description]
Evoxanthine is an alkaloid that has been found in O. renieri and has antimalarial and anticancer activities. It is active against P. falciparum with an IC50 value of 67.6 μg/ml. Evoxanthine decreases proliferation of nine sensitive and drug-resistant cancer cell lines (IC50s = 6.11-80.99 μM). | [Uses]
Evoxanthine is a compound that can be isolated from the stem bark of Pleiocarpa pycnantha[1]. | [References]
[1] Ndongo JT, et al. Carbazole-, Aspidofractinine-, and Aspidocarpamine-Type Alkaloids from Pleiocarpa pycnantha. J Nat Prod. 2018 May 25;81(5):1193-1202. DOI:10.1021/acs.jnatprod.7b00958 |
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