| Identification | Back Directory | [Name]
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-phenylethyl)-, (5α)- | [CAS]
4778-94-3 | [Synonyms]
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-phenylethyl)-, (5α)- | [Molecular Formula]
C24H25NO4 | [MOL File]
4778-94-3.mol | [Molecular Weight]
391.46 |
| Chemical Properties | Back Directory | [Melting point ]
80-90 °C | [Boiling point ]
605.1±55.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [solubility ]
Acetonitrile: Soluble
DMSO: Soluble
Methanol: Soluble | [pka]
9.16±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
N-Phenethylnoroxymorphone is an opioid compound. N-Phenethylnoroxymorphone enhances morphine-induced analgesia in rats. N-Phenethylnoroxymorphone can be used for research on neurological diseases[1]. | [References]
[1] Ben Haddou T, et al. Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity. PLoS One. 2014 Jun 11;9(6):e99231. DOI:10.1371/journal.pone.0099231
[2] Selfridge BR, et al. Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. J Med Chem. 2015 Jun 25;58(12):5038-52. DOI:10.1021/acs.jmedchem.5b00426 |
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