| Identification | Back Directory | [Name]
Furo[2,3-c]pyridine-5-methanol (9CI) | [CAS]
478148-60-6 | [Synonyms]
Furo[2,3-c]pyridine-5-Methanol
furo[2,3-c]pyridin-5-ylmethanol
Furo[2,3-c]pyridine-5-methanol (9CI) | [Molecular Formula]
C8H7NO2 | [MDL Number]
MFCD11109707 | [MOL File]
478148-60-6.mol | [Molecular Weight]
149.15 |
| Chemical Properties | Back Directory | [Boiling point ]
289.8±25.0 °C(Predicted) | [density ]
1.315±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
13.36±0.10(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of furo[2,3-c]pyridin-5-ylmethanol from the compound (CAS: 478148-59-3): C14 (770 mg, 3.48 mmol) was dissolved in 10 mL of methanol. A 2 N sodium hydroxide solution (3 mL, 6 mmol) was added to the solution and the reaction mixture was stirred at room temperature for 1.5 hours. After completion of the reaction, the solution was concentrated to dryness under vacuum. Water (20 mL) was added to the residue and extracted with dichloromethane (4 x 10 mL). The organic layers were combined, dried with anhydrous potassium carbonate, filtered, and concentrated under vacuum to give furo[2,3-c]pyridin-5-ylmethanol (C16) as a white solid in 90% yield. Elemental analysis (C8H7NO2) Calculated values: C, 64.42; H, 4.73; N, 9.39. Measured values: C, 64.60; H, 4.56; N, 9.44. | [References]
[1] Patent: US2003/45540, 2003, A1
[2] Patent: WO2004/52894, 2004, A1. Location in patent: Page 34 |
|
| Company Name: |
China Langchem Inc.
|
| Tel: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
SynAsst Chemical.
|
| Tel: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
| Company Name: |
NovoChemy Ltd.
|
| Tel: |
86-(0)21-31261262 373522135 |
| Website: |
www.novochemy.com |
|