| | Identification | Back Directory |  | [Name] 
 FAM alkyne, 6-isomer
 |  | [CAS] 
 478801-49-9
 |  | [Synonyms] 
 FAM alkyne, 6-isomer
 FAMalkyne,6-isomer, >97%
 3',6'-Dihydroxy-3-oxo-N-(prop-2-yn-1-yl)-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
 Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxamide, 3',6'-dihydroxy-3-oxo-N-2-propyn-1-yl-
 |  | [Molecular Formula] 
 C24H15NO6
 |  | [MDL Number] 
 MFCD28505570
 |  | [MOL File] 
 478801-49-9.mol
 |  | [Molecular Weight] 
 413.38
 | 
 | Chemical Properties | Back Directory |  | [Boiling point ] 
 722.3±60.0 °C(Predicted)
 |  | [density ] 
 1.58±0.1 g/cm3(Predicted)
 |  | [solubility ] 
 Soluble in DMSO, DMF, DCM
 |  | [pka] 
 9.32±0.20(Predicted)
 |  | [Appearance] 
 yellow solid
 | 
 | Hazard Information | Back Directory |  | [Description] 
 FAM (fluorescein) alkyne is a high purity (96%) 6-isomer with significant aqueous solubility. Alkyne enables copper-catalyzed Click chemistry.
 |  | [Uses] 
 FAM alkyne, 6-isomer is a click chemistry regent that can be used in 1,3-dipolar cycloaddition with azido-labeled compound[1].
 |  | [References] 
 [1] Tae Seok Seo, et al. Click chemistry to construct fluorescent oligonucleotides for DNA sequencing. J Org Chem. 2003 Jan 24;68(2):609-12. DOI:10.1021/jo026615r
 |  | [Abs/Em Maxima] 
 492/517 nm
 |  | [Fluoresene quantum yield] 
 0.93
 |  | [Extinction Coefficient] 
 74000
 |  | [CF260] 
 0.22
 |  | [CF280] 
 0.17
 | 
 |  |