ChemicalBook--->CAS DataBase List--->478801-49-9

478801-49-9

478801-49-9 Structure

478801-49-9 Structure
IdentificationBack Directory
[Name]

FAM alkyne, 6-isomer
[CAS]

478801-49-9
[Synonyms]

FAM alkyne, 6-isomer
FAMalkyne,6-isomer, >97%
3',6'-Dihydroxy-3-oxo-N-(prop-2-yn-1-yl)-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxamide, 3',6'-dihydroxy-3-oxo-N-2-propyn-1-yl-
[Molecular Formula]

C24H15NO6
[MDL Number]

MFCD28505570
[MOL File]

478801-49-9.mol
[Molecular Weight]

413.38
Chemical PropertiesBack Directory
[Boiling point ]

722.3±60.0 °C(Predicted)
[density ]

1.58±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DMF, DCM
[pka]

9.32±0.20(Predicted)
[Appearance]

yellow solid
Hazard InformationBack Directory
[Description]

FAM (fluorescein) alkyne is a high purity (96%) 6-isomer with significant aqueous solubility. Alkyne enables copper-catalyzed Click chemistry.
[Uses]

FAM alkyne, 6-isomer is a click chemistry regent that can be used in 1,3-dipolar cycloaddition with azido-labeled compound[1].
[References]

[1] Tae Seok Seo, et al. Click chemistry to construct fluorescent oligonucleotides for DNA sequencing. J Org Chem. 2003 Jan 24;68(2):609-12. DOI:10.1021/jo026615r
[Abs/Em Maxima]

492/517 nm
[Fluoresene quantum yield]

0.93
[Extinction Coefficient]

74000
[CF260]

0.22
[CF280]

0.17
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